865565-70-4Relevant academic research and scientific papers
A concise synthesis of (-)-cytoxazone and (-)-4-epi-cytoxazone using chlorosulfonyl isocyanate
Kim, In Su,Kim, Ji Duck,Ryu, Chae Baek,Zee, Ok Pyo,Jung, Young Hoon
, p. 9349 - 9358 (2007/10/03)
A concise synthesis of (-)-cytoxazone and its stereoisomer (-)-4-epi-cytoxazone, novel cytokine modulators, has been accomplished each in six steps from readily available p-anisaldehyde with good diastereoselectivity. Key steps in the synthesis include th
Regioselective and diastereoselective amination with use of chlorosulfonyl isocyanate: A short and efficient synthesis of (-)-cytoxazone
Kim, Ji Duck,Kim, In Su,Jin, Cheng Hua,Zee, Ok Pyo,Jung, Young Hoon
, p. 4025 - 4028 (2007/10/03)
(Chemical Equation Presented) The total synthesis of (-)-cytoxazone 1 was achieved in six linear steps (34% overall yield) from p-anisaldehyde. The key steps in this route are the regioselective and stereoselective introduction of a N-protected amine grou
