865620-21-9

Upstream product

• 653-37-2 perfluorobenzaldehyde 
• 134030-22-1 N,N'-bis(2,6-diisopropylphenyl)ethane-1,2-diamine 
• 74663-75-5 1,2-bis(2,6-diisopropylphenylimino)ethane 
• 24544-04-5 2,6-diisopropylbenzenamine 

Relevant academic research and scientific papers

Synthesis of pentafluorobenzene-based NHC adducts and their catalytic activity in the microwave-assisted reactions of aldehydes

N-Heterocyclic carbenes (NHCs) have been widely used in organometallic chemistry as ligands, as well as standalone organocatalysts in various reactions, mostly using aromatic aldehydes as substrates. We have previously demonstrated the efficiency of azolium-2-carboxylate zwitterions in the hydroxymethylation of aldehydes, especially aliphatic aldehydes, under microwave irradiation. In the present work, we report a series of pentafluorobenzene-based NHC adducts and their efficiency in the hydroxymethylation and self-condensation of aliphatic and aromatic aldehydes using microwave irradiation. The free carbenes are released under the reaction conditions and 1,3-dimesityl-2-(perfluorophenyl)imidazolidine and 1,3-bis(2,6-dimethylphenyl)-2-(perfluorophenyl)imidazolidine proved to be the most potent precatalysts.

N-Heterocyclic carbene adducts of orthopalladated triarylphosphite complexes

Carbene adducts of orthopalladated triarylphosphite complexes have been synthesised and characterised. The structures of three of these complexes were determined by single-crystal X-ray analysis. The complexes are active in the Suzuki coupling of a range of aryl bromide substrates. The Royal Society of Chemistry 2005.