86576-73-0Relevant academic research and scientific papers
PhI(OCOCF3)2-Mediated Construction of a 2-Spiropseudoindoxyl Skeleton via Cascade Annulation of 2-Sulfonamido-N-phenylpropiolamide Derivatives
Zhang, Bobo,Zhang, Xiang,Hu, Bei,Sun, Desong,Wang, Senlin,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 902 - 905 (2017)
A cascade annulation of 2-sulfonamido-N-phenylpropiolamide derivatives leading to the construction of the 2-spiropseudoindoxyl skeleton was realized under mild conditions with phenyliodine(III) bis(trifluoroacetate) (PIFA) as the sole oxidant. This metal-
Photo-mediated synthesis of halogenated spiro[4,5]trienones of: N-aryl alkynamides with PhI(OCOCF3)2 and KBr/KCl
Duan, Chunying,Jiang, Linlin,Jin, Kun,Li, Yaming,Liu, Tong,Wang, Jiaao,Zhang, Rong
supporting information, p. 1933 - 1939 (2020/03/23)
A novel and convenient photo-mediated halogenated spirocyclization of N-(p-methoxyaryl)propiolamides has been developed. The photolysis of phenyliodine bis(trifluoroacetate) (PIFA) as an iodination reagent led to iodinated ipso-cyclization under the irrad
Copper/Nafion-Catalyzed Hydroarylation Process Involving Ketenimine Intermediates: A Novel and Synthetic Approach to 4-Sulfonamidoquinoline-2-ones and Derivatives Thereof
Reichart, Benedikt,Guedes De La Cruz, Gema,Zangger, Klaus,Kappe, C. Oliver,Glasnov, Toma
supporting information, p. 50 - 55 (2016/01/25)
A copper(II)/NafionNR50-catalyzed cascade is demonstrated, wherein in situ keteneimine formation and hydroarylation processes are involved. Various substituted 4-sulfonamidoquinolin-2-ones and various derivatives thereof were obtained. The robust toluenesulfonamide protecting group can be removed on demand in a mild light-promoted process to provide access to otherwise difficult to obtain 4-aminoquinolin-2-ones.
