865786-21-6Relevant articles and documents
Targeting RAS-RAF pathway significantly improves antitumor activity of Rigosertib-derived platinum(IV) complexes and overcomes cisplatin resistance
Liu, Zhikun,Wang, Meng,Wang, Hengshan,Fang, Lei,Gou, Shaohua
, (2020)
RAS-RAF pathway presents a valuable target for the cancer treatment due to its important roles in the regulation of tumor proliferation, apoptosis and the obtained resistance. To explore such target a RAS/CRAF interference agent, was therefore conjugated