866003-66-9Relevant academic research and scientific papers
Arabinose-derived ketones as catalysts for asymmetric epoxidation of alkenes
Shing, Tony K. M.,Leung, Gulice Y. C.,Luk, To
, p. 7279 - 7289 (2005)
Readily available arabinose-derived ketones, containing a tunable butane-2,3-diacetal as the steric blocker, displayed increasing enantioselectivity (up to 90% ee) with the size of the acetal alkyl group in catalytic asymmetric epoxidation of trans-disubstituted and trisubstituted alkenes. The stereochemical communication between our ketone catalysts and the alkene substrates is mainly due to steric effect, and electronic effect involving π-π interaction between phenyl groups of substrate and of catalyst did not appear to be operative in our system.
