866005-62-1Relevant articles and documents
Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture
Nasim, Shama,Guzman, Monica L.,Jordan, Craig T.,Crooks, Peter A.
, p. 4879 - 4883 (2011/09/16)
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8) was previously identified as an antileukemic agent exhibiting no evident toxicity toward normal hematopoietic cells. An SAR study has been carried out to examine the effect of varying the C-2 and