866005-62-1

Upstream product

• 220298-96-4 4‐(tert‐butoxycarbonylamino)benzylamine 
• 144072-29-7 tert-butyl N-[4-(hydroxymethyl)phenyl]carbamate 
• 916578-53-5 tert-butyl (4-(chloromethyl)phenyl)carbamate 
• 168050-39-3 [(4-Aminophenyl)methyl]carbamic acid,phenylmethyl ester 
• 4403-71-8 (4-aminomethyl)aniline 
• 630125-51-8 [4-(benzyloxycarbonylamino-methyl)phenyl]-carbamic acid tert-butyl ester 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1346771-62-7 C₁₇H₂₂ClN₃O₄S 
• 1346771-61-6 C₁₇H₂₂BrN₃O₄S 
• 1346771-63-8 C₁₈H₂₃N₃O₄S 
• 1346771-64-9 C₁₇H₂₃N₃O₄S 
• 882430-31-1 {4-[(4-tert-butyl-benzyloxythiocarbonylamino)-methyl]-phenyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture

4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8) was previously identified as an antileukemic agent exhibiting no evident toxicity toward normal hematopoietic cells. An SAR study has been carried out to examine the effect of varying the C-2 and

Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists

The structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. A docking model of potent antagonist 2 with the sensor region of TRPV1 is proposed.