866022-28-8 Usage
Uses
Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.
Check Digit Verification of cas no
The CAS Registry Mumber 866022-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,0,2 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 866022-28:
(8*8)+(7*6)+(6*6)+(5*0)+(4*2)+(3*2)+(2*2)+(1*8)=168
168 % 10 = 8
So 866022-28-8 is a valid CAS Registry Number.
866022-28-8Relevant articles and documents
Aromatic polyketone compounds, and synthesis method and application thereof
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Paragraph 0238; 0346-0355, (2021/07/01)
The invention discloses a synthesis method of aromatic polyketone products and analogues thereof. Intermolecular Diels-Alder reaction is performed on a formula 1a and a formula 2a to prepare a formula 3a, and a formula 4a is protected by using an ether ad