866050-58-0

Basic information

• Product Name: 3-(3-NITROPHENYL)-1,4-BENZOXAZEPIN-5(4H)-ONE
• Synonyms: 3-(3-NITROPHENYL)-1,4-BENZOXAZEPIN-5(4H)-ONE;3-(3-nitrophenyl)-4,5-dihydro-1,4-benzoxazepin-5-one
• CAS NO: 866050-58-0
• Molecular Formula: C₁₅H₁₀N₂O₄
• Molecular Weight: 282.25
• Mol File: 866050-58-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3-NITROPHENYL)-1,4-BENZOXAZEPIN-5(4H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-NITROPHENYL)-1,4-BENZOXAZEPIN-5(4H)-ONE(866050-58-0)
• EPA Substance Registry System: 3-(3-NITROPHENYL)-1,4-BENZOXAZEPIN-5(4H)-ONE(866050-58-0)

Safety Data

• Hazardous Substances Data: 866050-58-0(Hazardous Substances Data)

Upstream product

• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 65-45-2 salicylamide 
• 866019-39-8 2-(2-(3-nitrophenyl)-2-oxoethoxy)benzamide 

Relevant articles and documents

Synthesis and tranquillizing effect of new 1,4-benzoxazepines

A SERIES of new 1,4-benzoxazepin-5(4H)-ones was prepared by alkylation of salicylamides with phenacyl bromides followed by cyclodehydration of the resulting amides. Treatment of the 1,4-benzoxazepine-5(4H)-ones with phosphorus pentasulphide afforded the corresponding 1,4-benzoxazepine-5(4H)-thiones. N-alkylation of the 1,4-benzoxazepin-5(4H)-ones and S-alkylation of the 1,4-benzoxazepine-5(4H)-thiones were described. Some of the new compounds were subjected to preliminary screening for their tranquilizing effect.