866138-98-9

Upstream product

• 197229-94-0 (tert-butyl)(dimethyl){3-[(2S)-oxiran-2-yl]propoxy}silane 
• 89872-57-1 (2S)-2,5-dihydroxy-1-tosyloxypentane 
• 58879-34-8 (S)-5-tosyloxypentan-4-olide 
• 86771-48-4 (4R)-4-[(4-methoxybenzyl)oxymethyl]-γ-butyrolactone 
• 52813-63-5 (5R)-2,3,4,5-tetrahydro-5-hydroxymethyl-2-furanone 
• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 
• 866138-87-6 ethyl (2E,4R,6R,7S,10S,12E)-6-((R)-4-benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxytetradeca-2,12-dienoate 
• 866138-95-6 ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate 
• 866138-77-4 (R)-4-benzyl-3-((R)-4-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)pentanoyl)oxazolidin-2-one 
• 866138-78-5 ethyl (2E,4R)-7-((R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl)-4-(tert-butyldimethylsilyloxy)-7-oxohept-2-enoate 
• 866138-92-3 (4S,6E)-1-tert-butyldimethylsilyloxy-4-tert-butyldiphenylsilyloxy-6-octene 
• 866138-90-1 (R)-4-benzyl-3-((R)-4-(tert-butyldimethylsilyloxy)-5-hydroxypentanoyl)oxazolidin-2-one 
• 866138-91-2 (R)-5-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-oxo-pentanal 
• 866138-81-0 (4S,6E)-4-tert-butyldiphenylsilyloxy-6-octen-1-ol 

Relevant academic research and scientific papers

Synthesis of (-)-amphidinolide K fragment C9-C22

(Chemical Equation Presented) The key fragment (2a or 2b) in a total synthesis of the cytotoxic macrolide (-)-amphidinolide K (1) has been achieved from synthons C9-C14 (3) and C15-C22 (4), which have both been prepared from glutamic acid in good overall yields.