866229-22-3Relevant academic research and scientific papers
Lehualides A-D, metabolites from a Hawaiian sponge of the genus Plakortis
Sata, Noriko,Abinsay, Hazel,Yoshida, Wesley Y.,Horgen, F. David,Sitachitta, Namthip,Kelly, Michelle,Scheuer, Paul J.
, p. 1400 - 1403 (2005)
A collection of an undescribed marine sponge of the genus Plakortis yielded four new "polyketide-derived" metabolites, lehualides A-D (1-4). The structures of compounds 1-4 were elucidated by interpretation of spectral data. Compound 2 demonstrated cytotoxicity against an ovarian cancer cell line, while compound 4 was active against both ovarian cancer and leukemia cell lines.
