86627-06-7

Upstream product

• 504-17-6 4,6-dihydroxy-2-mercaptopyrimidine 
• 824-94-2 p-methoxybenzyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 91759-32-9 2-Thiobarbituric acid 

Downstream Products

• 1253847-64-1 2-[3-(2-tert-butoxycarbonylaminoacetylamino)-4-methoxybenzyl sulfanyl]-8-ethyl-9-methyl-6-morpholino-9H-purine 
• 1253847-27-6 2-(3-acetylamino-4-methoxybenzylsulfanyl)-8-ethyl-9-methyl-6-morpholino-9H-purine 
• 1253848-91-7 8-ethyl-9-methyl-6-morpholino-2-(3-nitro-4-methoxybenzylsulfanyl)-9H-purine 
• 1253847-02-7 2-(3-amino-4-methoxybenzylsulfanyl)-8-ethyl-9-methyl-6-morpholino-9H-purine 
• 869119-26-6 5-amino-2-(4-methoxybenzylsulfanyl)-6-methylamino-4-morpholinopyrimidine 
• 869119-61-9 2-(4-methoxybenzylsulfanyl)-4-methylamino-6-morpholino pyrimidine 
• 869119-60-8 4-chloro-2-(4-methoxybenzylsulfanyl)-6-methylaminopyrimidine 
• 1253847-01-6 8-ethyl-2-(4-methoxybenzylsulfanyl)-9-methyl-6-morpholino-9H-purine 
• 86627-09-0 2-p-Methoxybenzylthio-4-chloro-6-(N-methyl-2,3-xylidino)-pyrimidine 
• 86627-08-9 <4-chloro-6-<(2,3-dimethylphenyl)amino>-2-(4-methoxybenzyl)thio>pyrimidine 
• 166751-67-3 4-amino-6-chloro-2-(4-methoxyphenylmethylthio)-pyrimidine 
• 86627-07-8 4,6-dichloro-2-(4-methoxyphenylmethylthio)-pyrimidine 

Relevant academic research and scientific papers

PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME

Disclosed are: a novel purine derivative, a composition thereof, a method for treating tumor using the purine derivative, and an antitumor agent using the purine derivative. Specifically disclosed is a compound represented by formula (I), or a pharmaceuti

Pyrazole compounds useful as protein kinase inhibitors

This invention describes novel pyrazole compounds of formula IIIa: wherein R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx/sup

Pyrimidine-thioalkyl and alkylether compounds

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I and pyrimidine-thioalkyl and alkylethers of Formula IA, namely the compounds of Formula I whereR4 is selected from the group consisting of -H or -NRsub

Pyrimidine thioethers: A novel class of HIV-1 reverse transcriptase inhibitors with activity against BHAP-resistant HIV

A series of pyrimidine thioethers was synthesized and evaluated for inhibitory properties against wild-type HIV-1 reverse transcriptase (RT) and an RT carrying the resistance-conferring mutation P236L. Modifications of both the pyrimidine and the function

Pyrimidine and s-triazine derivatives with antilipidemic activity

Pyrimidine and s-triazine derivatives of formula (I) (I) in which X=CH or N; Y=for example halogen, alkoxy; W=for example -S-CH2-COOH, -O-CH2-COO alkyl, -NH-CH2-CONHCH2CH2OH; Z=for example 2,3-xylidino, and methods for the preparation thereof are described. The compounds show high antilipemic activity.

Novel pyrimidine and 1,3,5-triazine hypolipidemic agents

New compounds were synthesized by changing the substituents of a trisubstituted pyrimidine, i.e., [[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]acetic acid, a potent hypolipidemic agent, impaired, however, by a marked hepatomegaly-inducing effect. The structural variations led to the subsidence (14b, i.e., 4-chloro-2-(dimethylamino)-6-[(2,3-dimethylphenyl)amino]pyrimidine) or to the reduction (18b, [[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]amino]acetic acid) of said untoward effect but still maintained the hypolipidemic effect that, although markedly decreased, still proves significant for serum cholesterol and triglycerides (18b) or for serum triglycerides only (14b).