86631-57-4

Upstream product

• 299-42-3 ephedrine 
• 86631-56-3 (R)-2,2'-dibromomethyl-1,1'-binaphthalene 
• 54130-90-4 2,2'-di(bromomethyl)-1,1'-binaphthalene 

Downstream Products

• 19634-89-0 (R)-2,2'-dimethyl-1,1'-binaphthyl 
• 143971-08-8 (S,1S,2R)-2-azido-2'-<methyl>-1,1'-binaphthyl 
• 97781-24-3 (1R,2S)-2-[Methyl-(2'-methyl-[1,1']binaphthalenyl-2-ylmethyl)-amino]-1-phenyl-propan-1-ol 

Relevant academic research and scientific papers

REDUCTIVE CLEAVAGE OF AXIALLY DISYMMETRIC TERTIARY AMINES AND QUATERNARY AMMONIUM SALTS BY LITHIUM ALUMINIUM HYDRIDE. SYNTHESIS OF NEW 1,1'-BINAPHTHYL SUBSTITUTED AMINES

Axially disymmetric tertiary amines or quaternary ammonium salts A are synthesized by double alkylation of primary or secundary amines with racemic or optically pure 2,2'-bis(bromomethyl)-1,1'-binaphthyl.Their reductive cleavage by lithium aluminium hydri

METHODE SIMPLE DE SYNTHESE D'AGENTS DE TRANSFERT CHIRAUX PAR ACTION D'UN AGENT ALKYLANT A SQUELETTE BINAPHTYLE-1,1'

A general way for introducing axial chirality in phase transfer catalysts, by quaternarization with 2,2'-bis(bromomethyl)-1,1'-binaphtyl, is described and applied to l(-) ephedrine.One of the resulting catalysts gives 37 percent ee in epoxydation of chalcone.