866331-62-6

Upstream product

• 380429-39-0 (2R)-2-amino-2-(hydroxymethyl)pentanedioic acid 
• 866331-60-4 (4R,5S)-3-benzyl 4-methyl 5-((R)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-oxopyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-58-0 (1S,7aR)-1-((R)-Benzyloxycarbonylamino-methoxycarbonyl-methyl)-3,3-dimethyl-5-oxo-dihydro-pyrrolo[1,2-c]oxazole-7a-carboxylic acid methyl ester 
• 866331-59-1 (4R,5S)-5-((R)-2-Methoxycarbonyl-5-oxo-pyrrolidin-2-yl)-2,2-dimethyl-oxazolidine-3,4-dicarboxylic acid 3-benzyl ester 4-methyl ester 
• 866331-54-6 (2R)-1-tert-butyl 2-methyl 2-((4R,5S)-5-(methoxycarbonyl)-2-thioxo-1,3-dioxolan-4-yl)-5-oxopyrrolidine-1,2-dicarboxylate 
• 866331-53-5 (2R)-1-tert-butyl 2-methyl 2-((1R,2S)-2-(methoxycarbonyl)-1,2-dihydroxyethyl)-5-oxopyrrolidine-1,2-dicarboxylate 
• 866331-51-3 (2R)-1-tert-butyl 2-methyl 2-(tert-butyldimethylsilyloxymethyl)-5-oxopyrrolidine-1,2-dicarboxylate 
• 866331-70-6 (1S,7aR)-methyl 1-((1R)-(methoxycarbonyl)azidomethyl)hexahydro-3,3-dimethyl-5-oxopyrrolo[1,2-c]oxazole-7a-carboxylate 
• 866331-52-4 (2R)-1-tert-butyl 2-methyl 2-((E)-2-(methoxycarbonyl)vinyl)-5-oxopyrrolidine-1,2-dicarboxylate 
• 866331-55-7 (R)-2-((4R,5S)-5-Methoxycarbonyl-2-thioxo-[1,3]dioxolan-4-yl)-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 866331-56-8 (2R)-methyl 2-((1S,2R)-2-(methoxycarbonyl)-2-azido-1-hydroxyethyl)-5-oxopyrrolidine-2-carboxylate 
• 866331-68-2 (2R)-1-tert-butyl 2-methyl 2-(hydroxymethyl)-5-oxopyrrolidine-1,2-dicarboxylate 
• 866331-49-9 (2R)-1-tert-butyl 2-formyl-5-oxopyrrolidine-1,2-dicarboxylate methyl ester 
• 866331-50-2 (R)-2-Hydroxymethyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 

Downstream Products

• 866331-75-1 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-(2-(tert-butyldimethylsilyloxymethyl)-2-hydroxyethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-76-2 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-(2-(tert-butyldimethylsilyloxymethyl)-2-azidoethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-80-8 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((R)-2-(methoxycarbonyl)-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-79-5 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((S)-2-(methoxycarbonyl)-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-85-3 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((R)-2-hydroxymethyl-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-87-5 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((S)-2-hydroxymethyl-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-78-4 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((R)-2-(tert-butyldimethylsilyloxymethyl)-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 
• 866331-77-3 (4R,5S)-3-benzyl 4-methyl 5-((2R,5S)-1-(tert-butoxycarbonyl)-2-(methoxycarbonyl)-5-((S)-2-(tert-butyldimethylsilyloxymethyl)-2-(4-benzyloxy-3,5-dichlorobenzamido)ethyl)pyrrolidin-2-yl)-2,2-dimethyloxazolidine-3,4-dicarboxylate 

Relevant academic research and scientific papers

Total synthesis of (-)-kaitocephalin

(Chemical Equation Presented) Total synthesis of the potent AMPA/KA receptor antagonist (-)-kaitocephalin (1) and its three diastereomers has been accomplished. The synthesis features strictly substrate-controlled operations to α-formylglutamate 3 startin

Stereoselective synthesis of 2,5-di- and 2,2,5-trisubstituted pyrrolidines by allylation reacton of acyliminium ion

-Allylation reactions of allytrimethylsilane and an allylcopper reagent to acyliminium ions derived from several 2-monosubstituted and 2,2-disubstituted pyrrolidinones were examined. These reactions proceeded in a stereoselective manner to give the corresponding allylated adducts. The stereochemical outcomes of these reactions were dependent upon the allylating reagents or the structures of the acyliminium ions.