866343-47-7

Upstream product

• 326603-47-8 ethyl (3S)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]butanoate 

Downstream Products

• 866343-55-7 ethyl (2S,3R)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-2-hydroxybutanoate 
• 866343-42-2 ethyl (2R,3R)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-2-hydroxybutanoate 
• 866343-44-4 (3S,4S)-3-(allyloxy)-4-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]pentanal 
• 866343-63-7 (3R,4S)-3-(allyloxy)-4-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]pentanal 
• 866343-43-3 (2R,3S)-2-(allyloxy)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-butan-1-ol 
• 866343-60-4 (2S,3S)-2-(allyoxy)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-butan-1-ol 
• 866343-54-6 (3S,4S)-3-(allyloxy)-4-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]pentanenitrile 
• 866343-62-6 (3R,4S)-3-(allyoxy)-4-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]pentanenitrile 
• 866343-59-1 ethyl (2S,3R)-2-(allyoxy)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-butanoate 
• 866343-50-2 ethyl (2R,3R)-2-(allyloxy)-3-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-butanoate 
• 866343-41-1 (5S,6S,2E)-tert-butyl 6-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-5-hydroxyhept-2-enoate 
• 866343-48-8 (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-3-((4R,5R)-2,2-dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-butyric acid ethyl ester 
• 866343-64-8 tert-butyl (5R,6S,E)-5-(allyloxy)-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-hept-2-enoate 
• 866343-51-3 tert-butyl (5S,6S,E)-5-(allyloxy)-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-hept-2-enoate 

Relevant academic research and scientific papers

Synthetic routes towards cryptophycin unit A diastereomers

Unit A of cryptophycin 1 is a δ-hydroxy acid with four stereogenic centres. Our unit A synthesis introduces the first two stereogenic centres by a catalytic, asymmetric dihydroxylation, whereas the remaining two stereogenic centres are established by dias