866458-29-9Relevant academic research and scientific papers
Amino acid-derived hydroxamic acids as chiral ligands in the vanadium catalysed epoxidation
Malkov, Andrei V.,Bourhani, Zainaba,Kocovsky, Pavel
, p. 3194 - 3200 (2007/10/03)
New sulfonamide-derived hydroxamic acids 7-11 have been developed as chiral ligands for the V-catalysed asymmetric epoxidation, showing high reactivity at subzero temperatures and moderate to good enantioselectivity. The strong accelerating effect exhibited by the ligands of this type can be attributed to the sulfonamide functionality. A range of cinnamyl type allylic alcohols were epoxidised with up to 74% ee. The Royal Society of Chemistry 2005.
