866466-93-5Relevant academic research and scientific papers
Room temperature hydroalkylation of electron-deficient olefins: sp 3 C-H functionalization via a Lewis acid-catalyzed intramolecular redox event
Pastine, Stefan J.,McQuaid, Kevin M.,Sames, Dalibor
, p. 12180 - 12181 (2007/10/03)
A practical method for the intramolecular hydroalkylation of electron-deficient olefins has been developed. The direct transformation of benzylic, tertiary, and sterically hindered secondary sp3 C-H bonds into C-C bonds under the action of a catalytic amount of a variety of Lewis acids is described. The mechanism of these transformations is proposed to involve a tandem hydride transfer/cyclization sequence. Copyright
