86652-32-6Relevant academic research and scientific papers
STUDIES RELATED TO β-LACTAM ANTIBIOTICS. PART 8. A FACILE ACID-CATALYZED RING TRANSFORMATION OF 1-DETHIA-1-OXA-5-EPI-ISOANHYDROPENICILLINS INTO OXAZOLINONES
Sako, Magoichi,Akira, Kazuki,Hirota, Kosaku,Maki, Yoshifumi
, p. 1001 - 1004 (2007/10/02)
1-Dethia-1-oxa-5-epiisoanhydropenicillin (2) undergoes with ease an acid-catalyzed ring transformation by virtue of the participation of an acylamino side chain to give oxazolinone derivative (4), as a mixture of geometrical isomers, under mild conditions in an excellent yield.
