866538-93-4

Usage

Uses

Used in Pharmaceutical Research:
(3R,5S)-1-(2-Fluoro-4-nitrophenyl)-3,5-dimethylpiperazine is used as a research compound for exploring its potential applications in the development of new pharmaceuticals. Its unique structure and properties may offer advantages in the treatment of various diseases and conditions.
Used in Drug Development:
In the pharmaceutical industry, (3R,5S)-1-(2-Fluoro-4-nitrophenyl)-3,5-dimethylpiperazine is utilized as a lead compound in the design and synthesis of novel drugs. Its specific configuration and functional groups may contribute to the discovery of new therapeutic agents with improved efficacy and selectivity.
Further studies are required to determine the specific uses and potential benefits of (3R,5S)-1-(2-Fluoro-4-nitrophenyl)-3,5-dimethylpiperazine in various applications. Its unique structure and properties may pave the way for innovative solutions in the field of drug discovery and development.

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 21655-48-1 cis-2,6-dimethylpiperazine 

Downstream Products

• 866538-94-5 (2R,6S)-4-(2-Fluoro-4-nitro-phenyl)-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-00-6 (2S,6R)-4-(4-Amino-2-fluoro-phenyl)-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-06-2 (2S,6R)-4-[2-Fluoro-4-((R)-5-hydroxymethyl-2-oxo-oxazolidin-3-yl)-phenyl]-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-15-3 (2S,6R)-4-[4-((S)-5-Aminomethyl-2-oxo-oxazolidin-3-yl)-2-fluoro-phenyl]-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-03-9 (2S,6R)-4-(4-Benzyloxycarbonylamino-2-fluoro-phenyl)-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-12-0 (2S,6R)-4-[4-((R)-5-Azidomethyl-2-oxo-oxazolidin-3-yl)-2-fluoro-phenyl]-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-18-6 (2R,6S)-4-{4-[(S)-5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 866539-09-5 (2S,6R)-4-[2-Fluoro-4-((R)-5-methanesulfonyloxymethyl-2-oxo-oxazolidin-3-yl)-phenyl]-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Thiazolidine derivatives or salts thereof as an active ingredient an inhibitor Pim

PROBLEM TO BE SOLVED: To provide compounds which have excellent Pim inhibitory action and are useful as pharmaceuticals.SOLUTION: A compound is a thiazolidine derivative represented by the general formula (1) in the figure, or a salt thereof. (In the formula, X represents O or S; Rrepresents a hydrogen atom or a Calkyl group; Z, Z, Z, Z, Zand Zeach independently represent CH or N; Y represents an optionally substituted, divalent Caromatic hydrocarbon group or the like; Am represents a disubstituted amino group, or an optionally substituted, nitrogen-containing saturated heterocyclic group; and Rand Reach independently represent a hydrogen atom, a halogen atom, an alkyl group or the like.)

TRIAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE and INFLAMMATORY DISEASES

Novel triazolopyridine compounds are disclosed that have a formula represented by Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non- limiting example, ECM degradation, joint degradation and/or inflammation, and others.

Synthesis and SAR of novel oxazolidinones: Discovery of ranbezolid

Novel oxazolidinones were synthesized containing a number of substituted five-membered heterocycles attached to the 'piperazinyl-phenyl-oxazolidinone' core of eperezolid. Further, the piperazine ring of the core was replaced by other diamino-heterocycles.