Cas 866550-60-9,[(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

866550-60-9

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Product Name: [(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
Synonyms: [(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
CAS NO:866550-60-9
Molecular Formula:
Molecular Weight: 570.496
EINECS: N/A
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Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
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Solubility: N/A
CAS DataBase Reference: [(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: [(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(866550-60-9)
EPA Substance Registry System: [(2S,3S,5R)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid allyl ester (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester(866550-60-9)

Safety Data

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HazardClass: N/A
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Hazardous Substances Data: 866550-60-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 866550-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,5,5 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 866550-60:
(8*8)+(7*6)+(6*6)+(5*5)+(4*5)+(3*0)+(2*6)+(1*0)=199
199 % 10 = 9
So 866550-60-9 is a valid CAS Registry Number.

866550-60-9Upstream product

866550-60-9Downstream Products

866550-60-9Relevant academic research and scientific papers

Convenient and efficient approach to di- and trideoxyribonucleotide N3′→P5′ phosphoramidates

Tang, Xu,Huang, Cheng,Fu, Hua,Zhao, Yufen

, p. 1930 - 1932 (2005)

Arbuzov reaction of phenyl phosphorodichloridite with an equivalent of allyl alcohol and tert-butyl alcohol produced phenyl allyl H-phosphonate and the subsequent ester-exchange with various nucleosides produced nucleoside allyl H-phosphonates. Antherton-Todd reaction of the nucleoside allyl H-phosphonates with 3′-amino-3′-deoxythymidine yielded dideoxyribonucleotide N3′→P5′ phosphoramidates, and the repetition of this procedure provided trideoxyribonucleotide N3′→P5′ phosphoramidates. The method can be used for the synthesis of oligodeoxyribonucleotide N3′→P5′ phosphoramidates without any protection for all nucleosides. Georg Thieme Verlag Stuttgart.

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