866559-82-2

Basic information

• Product Name: 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile
• Synonyms: 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile
• CAS NO: 866559-82-2
• Molecular Formula: C14H19N3O2S
• Molecular Weight: 293.38456
• Mol File: 866559-82-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile(866559-82-2)
• EPA Substance Registry System: 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile(866559-82-2)

Safety Data

• Hazardous Substances Data: 866559-82-2(Hazardous Substances Data)

Usage

Chemical structure

A piperidine derivative containing a propylsulfonyl group and a pyridine ring.

Potential uses

Pharmaceutical and medicinal research.

Enzyme inhibition

Studied for its potential as an inhibitor of certain enzymes.

Disease treatment

Being explored for its potential in the treatment of various diseases and conditions.

Ongoing research

Research on this compound is ongoing.

Therapeutic agent

Being explored for its potential as a therapeutic agent in various applications.

Specific properties

The specific properties and potential uses of this compound are the subject of ongoing study and investigation.

Upstream product

• 10147-36-1 n-propanesulfonyl chloride 
• 767263-33-2 4-(pyridine-2-yl)piperidine-4-carbonitrile 

Relevant articles and documents

Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitors

Employing an iterative analogue library approach, novel potent and selective glycine transporter 1 (GlyT1) inhibitors containing a 4-pyridin-2-ylpiperidine sulfonamide have been discovered. These inhibitors are devoid of time-dependent CYP inhibition activity and exhibit improved aqueous solubility versus the corresponding 4-phenylpiperidine analogues.

Heteroaryl Piperidine Glycine Transporter Inhibitors

The present invention is directed to pyridyl, pyridazinyl, pyrimidinyl and pyrazinyl piperidine compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergi