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86658-78-8

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86658-78-8 Usage

General Description

The chemical compound "(2-Indol-3-ylethyl)((4-methylphenyl)sulfonyl)amine" is a specific molecule with the formula C19H20N2O2S. It contains an indole ring, which is a bicyclic aromatic structure, connected to an ethylamine group. Additionally, it has a sulfonamide group attached to a 4-methylphenyl group. (2-INDOL-3-YLETHYL)((4-METHYLPHENYL)SULFONYL)AMINE has potential applications in pharmaceutical research, as indole derivatives are known for their diverse biological activities, including anticancer, antimicrobial, and anti-inflammatory properties. The sulfonamide group also confers potential medicinal properties, as it is often found in drugs with antibacterial and diuretic effects. Therefore, this compound may be of interest in the development of new drugs or bioactive molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 86658-78-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,6,5 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 86658-78:
(7*8)+(6*6)+(5*6)+(4*5)+(3*8)+(2*7)+(1*8)=188
188 % 10 = 8
So 86658-78-8 is a valid CAS Registry Number.

86658-78-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-tosyltryptamine

1.2 Other means of identification

Product number -
Other names N-tosyl tryptamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86658-78-8 SDS

86658-78-8Downstream Products

86658-78-8Relevant articles and documents

Construction of the Pyrrolo[2,3- d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide

Matsuoka, Junpei,Kumagai, Hiroshi,Inuki, Shinsuke,Oishi, Shinya,Ohno, Hiroaki

, p. 9358 - 9363 (2019)

We achieved direct construction of the common pyrrolo[2,3-d]carbazole core of aspidosperma and malagasy alkaloids by a gold-catalyzed cascade cyclization of ynamide. This reaction involves intramolecular cyclization from indole to ynamide followed by trapping of the resulting iminium intermediate. Through the use of chiral gold complexes, an enantiomerically enriched pyrrolo[2,3-d]carbazole was obtained in up to 74% ee. This methodology was successfully applied to the asymmetric formal synthesis of vindorosine.

Rhodium-Catalyzed Stereoselective Cyclization of 3-Allenylindoles and N-Allenyltryptamines to Functionalized Vinylic Spiroindolenines

Becker, Antonia,Breit, Bernhard,Grugel, Christian P.

supporting information, p. 3788 - 3792 (2021/05/29)

Herein, we report a highly enantio- and diastereoselective rhodium-catalyzed cyclization of N-allenyltryptamines and 3-allenylindoles to 6-membered spirocyclic indolenines. This allylic addition methodology offers the advantage of using a comparably cheap commercially available ligand with low loadings of an affordable rhodium precursor. The products can be converted into functionalized spirooxindoles and spiroindolines, which are regarded as important building blocks for the synthesis of a lot of natural products with biological activities.

Evaluation and docking of indole sulfonamide as a potent inhibitor of α-glucosidase enzyme in streptozotocin –induced diabetic albino wistar rats

Taha, Muhammad,Imran, Syahrul,Salahuddin, Mohammed,Iqbal, Naveed,Rahim, Fazal,Uddin, Nizam,Shehzad, Adeeb,Khalid Farooq, Rai,Alomari, Munther,Mohammed Khan, Khalid

, (2021/03/26)

We have synthesized new hybrid class of indole bearing sulfonamide scaffolds (1–17) as α-glucosidase inhibitors. All scaffolds were found to be active except scaffold 17 and exhibited IC50 values ranging from 1.60 to 51.20 μM in comparison with

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