86658-85-7

Upstream product

• 17715-00-3 prop-2-ynylcyclohexane 

Downstream Products

• 1606987-23-8 (E)-1-(4-cyclohexylbut-2-en-1-yl)-1H-benzo[d]imidazole 
• 1606987-25-0 (Z)-1-(4-cyclohexylbut-2-en-1-yl)-1H-benzo[d]imidazole 
• 1422198-35-3 1-[(4-cyclohexylbut-1-en-2-yl)oxy]-1H-1,2,3-benzotriazole 
• 1352641-23-6 C₃₁H₄₀O 
• 1352641-51-0 C₃₁H₄₀O 
• 1301638-76-5 C₂₀H₃₂ 
• 1246893-14-0 C₂₆H₃₀N₂O₂ 

Relevant academic research and scientific papers

Iron-Catalyzed Contrasteric Functionalization of Allenic C(sp2)-H Bonds: Synthesis of α-Aminoalkyl 1,1-Disubstituted Allenes

An iron-catalyzed C-H functionalization of simple monosubstituted allenes is reported. An efficient protocol for this process was made possible by the use of a newly developed electron-rich and sterically hindered cationic cyclopentadienyliron dicarbonyl complex as the catalyst andN-sulfonyl hemiaminal ether reagents as precursors to iminium ion electrophiles. Under optimized conditions, the use of a mild, functional-group-tolerant base enabled the conversion of a range of monoalkyl allenes to their allenylic sulfonamido 1,1-disubstituted derivatives, a previously unreported and contrasteric regiochemical outcome for the C-H functionalization of electronically unbiased and directing-group-free allenes.

Copper-Catalyzed Propargylic Reduction with Diisobutylaluminum Hydride

A mild and efficient method for the synthesis of allenes through selective copper-catalyzed hydride addition to propargylic chlorides using commercially available diisobutylaluminum hydride has been developed. This transformation, which is promoted by a readily accessible N-heterocyclic carbene-copper complex, provides a wide range of new and versatile functionalized allenes in good to excellent yields with high regio- A nd stereoselectivities.