86660-66-4Relevant academic research and scientific papers
3-OXO-INDAZOLINE AND 4-OXO-DIHYDROQUINAZOLINE DERIVATIVES FROM ISATIC ACIDS
Alemagna, A.,Baldoli, C.,Licandro, E.,Maiorana, S.,Papagni, A.
, p. 5397 - 5402 (2007/10/02)
The coupling of diazonium salts from isatic acids with alkoxycarbonylmethylenephosphoranes leads directly to 3-oxo-indazolin-2-yl-(alkoxycarbonyl)methylenetriphenylphosphoranes, while coupling with methyl 2-chloroacetacetate gives 2-phenyl-glyoxylic acid.
o.FORMYLARYLAZOMETHYLENETRIPHENYLPHOSPHORANES: A FACILE THERMALLY PROMOTED REARRANGEMENT TO 3-OXO-INDAZOLINE AND 4-OXO-DIHYDROQUINAZOLINE DERIVATIVES
Alemagna, A.,Buttero, P. del,Licandro, E.,Maiorana, S.,Papagni, A.
, p. 3321 - 3330 (2007/10/02)
The o.formylarylazomethylenetriphenylphosphoranes carrying an electron withdrawing group on the ylidic carbon undergo thermal intramolecular cyclization to 3-oxo-indazolin-2-yl-methylenephosphorane derivatives.The latter compounds, and their 1-alkyl derivatives, in turn, undergo thermal and/or acid catalyzed rearrangement to 4-oxo-1,4-dihydroquinazoline derivatives and PPh3.Some possible reaction mechanisms are discussed, and some synthetic applications of the above reactions are shown.
3-Oxoindazolinylmethylenephosphoranes from Isatic Acids
Alemagna, Andreina,Buttero, Paola Del,Licandro, Emanuela,Maiorana, Stefano,Guastini, Carlo
, p. 337 - 338 (2007/10/02)
Coupling diazonium salts from isatic acids with alkoxycarbonylmethylenephosphoranes leads directly to 3-oxoindazolin-2-ylalkoxycarbonylmethylenephosphoranes.
