86671-68-3

Basic information

• Product Name: N-(2-methylphenyl)-N_⁽¹⁾-(5-mercapto-3-methyl-4H-1,2,4-triazol-4-yl)thiourea
• CAS NO: 86671-68-3
• Molecular Weight: 279.39
• Mol File: 86671-68-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-methylphenyl)-N_⁽¹⁾-(5-mercapto-3-methyl-4H-1,2,4-triazol-4-yl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methylphenyl)-N_⁽¹⁾-(5-mercapto-3-methyl-4H-1,2,4-triazol-4-yl)thiourea(86671-68-3)
• EPA Substance Registry System: N-(2-methylphenyl)-N_⁽¹⁾-(5-mercapto-3-methyl-4H-1,2,4-triazol-4-yl)thiourea(86671-68-3)

Safety Data

• Hazardous Substances Data: 86671-68-3(Hazardous Substances Data)

Upstream product

• 95-53-4 o-toluidine 
• 2741-12-0 N,N-dimethyl-N'-o-tolyl-thiourea 
• 20939-15-5 3-methyl-4-amino-5-mercapto-1,2,4-triazole 
• 614-69-7 2-tolyl isothiocyanate 

Downstream Products

• 86671-62-7 (3-Methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-o-tolyl-amine 

Relevant articles and documents

Use of tetramethylthiuram disulfide in synthesis of nitrogen-containing heterocyclic compounds

We have developed a method for synthesis of aryl isothiocyanates by means of thiocarbamoylation of aromatic amines by tetramethylthiuram disulfide followed by degradation of the intermediate N(1)-aryl-N,N- dimethylthiourea by concentrated HCl. We have shown that thiocarbamoylation of 4-amino-5-ethyl-4H-1,2,4-triazole-3-thiol occurs at the 2 position of the triazole ring, while thiocarbamoylation of 4-amino-3-methyl-6-phenyl-4,5- dihydro-1,2,4-triazin-5-one leads to the dihetaryl-substituted thiourea. We consider the possibility of using N(1)-aryl-N,N-dimethylthioureas as analogs of isothiocyanates in reactions with N-nucleophiles. 2005 Springer Science+Business Media, Inc.