86671-69-4Relevant academic research and scientific papers
Use of tetramethylthiuram disulfide in synthesis of nitrogen-containing heterocyclic compounds
Demchenko,Yanchenko,Kisly,Lozinskii
, p. 668 - 672 (2007/10/03)
We have developed a method for synthesis of aryl isothiocyanates by means of thiocarbamoylation of aromatic amines by tetramethylthiuram disulfide followed by degradation of the intermediate N(1)-aryl-N,N- dimethylthiourea by concentrated HCl. We have shown that thiocarbamoylation of 4-amino-5-ethyl-4H-1,2,4-triazole-3-thiol occurs at the 2 position of the triazole ring, while thiocarbamoylation of 4-amino-3-methyl-6-phenyl-4,5- dihydro-1,2,4-triazin-5-one leads to the dihetaryl-substituted thiourea. We consider the possibility of using N(1)-aryl-N,N-dimethylthioureas as analogs of isothiocyanates in reactions with N-nucleophiles. 2005 Springer Science+Business Media, Inc.
A Convenient and Novel Synthesis of 1,2,4-Triazolo-thiadiazoles as Potential Pesticides
Chaturvedi, Bandana,Tiwari, Nirupama,Nizamuddin
, p. 1229 - 1232 (2007/10/02)
6-Arylamino-1,2,4-triazolo-thiadiazoles (IV) were synthesized by cyclo-dehydro-sulphurization of corresponding thioureas (III), which in turn were prepared by the condensation of N-amino-3-mercapto-1,2,4-triazoles (II) and aryl isothiocyanates (I) in dry dimethylformamide.These triazolo thiadiazoles (IV) were screened for their fungicidal activities of A. niger and H. oryzae.
