866774-34-7Relevant academic research and scientific papers
Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes
Bebernitz, Gregory R.,Beaulieu, Valerie,Dale, Bethany A.,Deacon, Richard,Duttaroy, Alokesh,Gao, Jiaping,Grondine, Melissa S.,Gupta, Ramesh C.,Kakmak, Mesut,Kavana, Michael,Kirman, Louise C.,Liang, Jinsheng,Maniara, Wieslawa M.,Munshi, Siralee,Nadkarni, Sunil S.,Schuster, Herbert F.,Stams, Travis,St. Denny, Irene,Taslimi, Paul M.,Vash, Brian,Caplan, Shari L.
experimental part, p. 6142 - 6152 (2010/02/28)
Type 2 diabetes is a polygenic disease which afflicts nearly 200 million people worldwide and is expected to increase to near epidemic levels over the next 10-15 years. Glucokinase (GK) activators are currently under investigation by a number of pharmaceu
