86680-32-2

Basic information

• Product Name: citrusinine I
• Synonyms: citrusinine I
• CAS NO: 86680-32-2
• Molecular Formula: C₁₆H₁₅NO₅
• Molecular Weight: 301.297
• Mol File: 86680-32-2.mol

Chemical Properties

• Melting Point: 205-208 °C
• Boiling Point: 567.5°C at 760 mmHg
• Flash Point: 297°C
• Appearance: /
• Density: 1.378g/cm³
• Vapor Pressure: 1.75E-13mmHg at 25°C
• Refractive Index: 1.646
• PKA: 7.51±0.20(Predicted)
• CAS DataBase Reference: citrusinine I(CAS DataBase Reference)
• NIST Chemistry Reference: citrusinine I(86680-32-2)
• EPA Substance Registry System: citrusinine I(86680-32-2)

Safety Data

• Hazardous Substances Data: 86680-32-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
Citrusinine I is used as a therapeutic agent for its potential anti-inflammatory and anti-cancer properties. It is believed to modulate various biological pathways and processes, thereby exhibiting inhibitory effects on inflammation and tumor growth.
Used in Antimicrobial Applications:
In the field of antimicrobial applications, citrusinine I is utilized as an antimicrobial agent to combat various types of microorganisms, contributing to the prevention and treatment of infections.
Used in Anti-diabetic Applications:
Citrusinine I is employed as an anti-diabetic agent, potentially aiding in the management and treatment of diabetes by influencing glucose metabolism and insulin sensitivity.
Used in Nutraceutical Applications:
As a component of citrus fruits, citrusinine I is used in the development of nutraceutical products, promoting overall health and wellness by providing antioxidant support and contributing to the prevention of various diseases.
Used in Cosmetic Applications:
In the cosmetic industry, citrusinine I may be used as an ingredient in skincare products for its antioxidant and anti-inflammatory properties, potentially benefiting skin health and appearance.

InChI:InChI=1/C16H15NO5/c1-17-13-8(5-4-6-9(13)18)15(20)12-10(19)7-11(21-2)16(22-3)14(12)17/h4-7,18-19H,1-3H3

Upstream product

• 130897-43-7 5-benzyloxy-1,3,4-trimethoxy-10-methyl-9(10H)-acridone 
• 548-93-6 3-hydroxyanthranilic acid 
• 149220-84-8 2-(2-benzyloxyphenylamino)-3,4,6-trimethoxy-N,N-dimethylbenzamide 
• 149220-83-7 2-(2-hydroxyphenylamino)-3,4,6-trimethoxy-N,N-dimethylbenzamide 
• 149220-85-9 3-hydroxy-2-(2,3,5-trimethoxyphenylamino)benzoic acid 
• 149220-82-6 2-iodo-3,4,6-trimethoxy-N,N-dimethylbenzamide 
• 149220-81-5 2,4,5-trimethoxy-N,N-dimethylbenzamide 
• 490-64-2 asaronic acid 
• 149220-86-0 5-benzyloxy-1-hydroxy-3,4-dimethoxy-10-methyl-9(10H)-acridone 
• 130897-42-6 5-benzyloxy-1,3,4-trimethoxy-9(10H)-acridone 
• 130897-39-1 5-hydroxy-1,3,4-trimethoxy-9(10H)-acridone 
• 23030-39-9 1-bromo-2,3,5-trimethoxybenzene 

Downstream Products

• 128364-25-0 1-Hydroxy-3,4,5-trimethoxy-10-methyl-10H-acridin-9-one 

Relevant articles and documents

Syntheses of the acridone alkaloid citrusinine-I and its derivatives

Citrusinine-I (1), a naturally occurring acridone alkaloid with potent antiviral activity, was synthesized for the first time, via a route involving Ullmann reaction, cyclization, and selective demethylation at the 1-position with boron trifluoride etherate and lithium bromide. 1,5,6-Trihydroxy-3-methoxy-9(10H)-acridone (2a) and 1,5,6-trihydroxy-3-methoxy-10-methyl-9(10H)-acridone (2b) were also synthesized.