866815-85-2Relevant academic research and scientific papers
Design and synthesis of a potent biotinylated Smac mimetic
Sun, Haiying,Nikolovska-Coleska, Zaneta,Yang, Chao-Yie,Wang, Shaomeng
, p. 7015 - 7018 (2005)
A biotinylated Smac mimetic (2) was designed based upon our previously reported potent, conformationally constrained Smac mimetic (1). Smac mimetic (2) was synthesized and determined to bind to XIAP protein with a high-affinity (Ki value of 13
