866823-72-5

Upstream product

• 866823-97-4 2-cyclopentyl-5-{[3-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzyl]oxy}-6,7-dimethylindan-1-one 
• 875414-67-8 ethyl 3'-{[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl}biphenyl-3-carboxylate 
• 41715-84-8 2-cyclopentyl-5-hydroxy-6,7-dimethyl-indan-1-one 
• 223799-25-5 2-(3-(bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxa borinane 

Downstream Products

• 888217-92-3 3'-{[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl} biphenyl-3-carboxylic acid chloride 

Relevant academic research and scientific papers

INDANONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutama

Biphenyl-indanones: Allosteric potentiators of the metabotropic glutamate subtype 2 receptor

We have identified and synthesized a series of biphenyl-carboxylic acid indanones as allosteric potentiators of the metabotropic glutamate receptor 2. Structure-activity relationship studies directed toward improving the potency and the brain to plasma ra