866915-57-3

Upstream product

• 866915-54-0 (S)-(2-aminophenyl)-(2-vinylpyrrolidin-1-yl)methanone 
• 53310-79-5 ethyl (2S)-2-(hyroxymethyl)pyrrolidine-1-carboxylate 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 103979-69-7 (S)-(-)-1-ethoxycarbonylpyrrolidine-2-carbaldehyde 
• 34897-85-3 o-azidobenzoyl chloride 
• 146405-59-6 (S)-2-vinylpyrrolidine 
• 112826-03-6 (S)-(-)-2-ethenyl-1-ethoxycarbonylpyrrolidine 
• 31162-13-7 2-azidobenzoic acid 
• 115393-77-6 tert-butyl (S)-2-vinylpyrrolidine-1-carboxylate 
• 866915-48-2 (S)-(2-nitrophenyl)-(2-vinylpyrrolidin-1-yl)methanone 

Relevant academic research and scientific papers

Intramolecular azide to alkene cycloadditions for the construction of pyrrolobenzodiazepines and azetidino-benzodiazepines

The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing pyrr

Effective synthesis of enantiopure [1,2,3]triazolo[1,5-a]- and pyrazolo[1,5-a]-pyrrolo[2,1-c][1,4]benzodiazepines by diastereoselective intramolecular azide and nitrilimine cycloadditions

The synthesis of new tetracyclic 1,4-benzodiazepinonic systems was performed in enantiopure form by totally diastereoselective intramolecular 1,3-dipolar cycloadditions. The absolute stereochemistry of the products was confirmed by X-ray crystallography a