866918-17-4Relevant academic research and scientific papers
Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption
Kv?rn?, Lisbet,Werder, Moritz,Hauser, Helmut,Carreira, Erick M.
, p. 6035 - 6053 (2007/10/03)
We have utilized our recently developed in vitro assay to address two key questions in the design of small-molecule cholesterol absorption inhibitors using ezetimibe, the only drug yet approved for the inhibition of cholesterol absorption in the small int
Carbohydrate sulfonyl chlorides for simple, convenient access to glycoconjugates
Kvaerno, Lisbet,Werder, Moritz,Hauser, Helmut,Carreira, Erick M.
, p. 1145 - 1148 (2007/10/03)
(Chemical Equation Presented) The use of carbohydrate sulfonyl chlorides is introduced as a new, facile glycoconjugation method which could find broad applications. We demonstrate the approach by synthesizing a number of glycosylated cholesterol absorptio
