866928-01-0

Basic information

• Product Name: (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclopropylmethyl-amine
• Synonyms: (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclopropylmethyl-amine
• CAS NO: 866928-01-0
• Molecular Weight: 416.95
• Mol File: 866928-01-0.mol

Chemical Properties

• CAS DataBase Reference: (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclopropylmethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclopropylmethyl-amine(866928-01-0)
• EPA Substance Registry System: (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclopropylmethyl-amine(866928-01-0)

Safety Data

• Hazardous Substances Data: 866928-01-0(Hazardous Substances Data)

Upstream product

• 866929-71-7 (3S,4R)-4-trifluoromethyl-piperidine-3,4-diol 
• 690266-28-5 methanesulfonic acid 2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl ester 

Downstream Products

• 866928-19-0 (2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-methyl-phenoxy}-ethyl)-cyclohexyl-cyclopropylmethyl-amine 

Relevant articles and documents

Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds

The present invention relates to alkyne compounds of general formula I wherein the groups and radicals A, B, W, X, Y, Z, R1 and R2 have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one alkyne according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.