867000-80-4

Upstream product

• 851121-41-0 (E)-(3R,4S)-4-Benzyloxy-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-pent-1-en-3-ol 
• 107-30-2 chloromethyl methyl ether 
• 851121-36-3 (E)-(S)-4-Benzyloxy-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-pent-1-en-3-one 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 867001-24-9 (E)-(2S,5R,6S)-6-Benzyloxy-5-methoxymethoxy-4-methyl-1-trityloxy-hept-3-en-2-ol 
• 851121-42-1 (R)-1-[(2S,3R)-3-((1S,2S)-2-Benzyloxy-1-methoxymethoxy-propyl)-3-methyl-oxiranyl]-2-trityloxy-ethanol 
• 867001-28-3 (2S,4R,5S,6S)-6-Benzyloxy-5-methoxymethoxy-4-methyl-1-trityloxy-heptane-2,4-diol 

Relevant academic research and scientific papers

Horner-Wadsworth-Emmons reactions as a facile entry to biogenetic key substructures

One-pot Horner-Wadsworth-Emmons reactions are used to synthesize α,β-enones with two configurationally independent stereogenic centers. These intermediates are used for the construction of polyketide and monosaccaride fragments. In particular, novel approaches to the branched pentoses mycarose and arcanose are described.