867013-00-1Relevant academic research and scientific papers
Ruthenium-Catalyzed Dual Dehydrogenative Silylation of C(sp3)-H Bonds: Access to Diverse Silicon-Centered Spirocycles
Wang, Zichen,Fang, Huaquan,Liu, Guixia,Huang, Zheng
supporting information, p. 7603 - 7607 (2021/10/12)
We report herein a pincer Ru-catalyzed dual intramolecular dehydrogenative silylation of primary C(sp3)-H bonds. The reaction features high efficiency, scalability, and good functional group tolerance, allowing a facile and atom-economical access to structurally diverse silicon-centered spirocycles, including unprecedented oxa-spirosilabiindanes and aza-spirosilabiindanes.
Efficient synthesis of substituted diarylsilanes
Gigler, Peter,Herrmann, Wolfgang A.,Kuehn, Fritz E.
experimental part, p. 1431 - 1432 (2010/09/14)
A highly efficient synthesis of substituted diarylsilanes is presented. The treatment of substituted arylbromides with tert-bu-tyllithium in diethyl ether at -78 °C, followed by the addition to dichlorodiethoxysilane at the same temperature, leads to the quantitative formation of diaryldiethoxysilane. Selective substitution of the chlorine atoms allows an aqueous work up in air. Subsequently, the diaryldiethoxysilane is reduced to the corresponding diarylsi-lane by stirring with lithium aluminum hydride in diethyl ether. The product is purified by bulb-to-bulb distillation. This method does not lead to any mono- or tri-substituted products and avoids handling gaseous and explosive dichlorosilane, which is a significant advantage over previously reported procedures. Georg Thieme Verlag Stuttgart.
