867021-89-4Relevant articles and documents
Design of β-secretase inhibitors by introduction of a mandelyl moiety in DAPT analogues
Pietrancosta, Nicolas,Quelever, Gilles,Laras, Younes,Garino, Cedrik,Burlet, Stephane,Kraus, Jean Louis
, p. 585 - 594 (2005)
We report the synthesis of two series of compounds with 3,5-difluoromandelyl-alanyl or 3,5-difluorophenylacetylalany1 backbones coupled to various heterocyclic or peptidic moieties. These two series of compounds were evaluated for their inhibitory propert