867033-63-4Relevant academic research and scientific papers
Phorboxazole compounds and methods of their preparation
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Page/Page column 46-47, (2009/02/11)
Novel macrolactone compounds, their methods of preparation, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the macrolactone compounds may be useful, inter alia, for treating various cancers, inducing apoptosis in malignant cells, or inhibiting cancer cell division.
(+)-Phorboxazole a synthetic studies. A highly convergent, second generation total synthesis of (+)-phorboxazole A
Smith III, Amos B.,Razler, Thomas M.,Ciavarri, Jeffrey P.,Hirose, Tomoyasu,Ishikawa, Tomoyasu
, p. 4399 - 4402 (2007/10/03)
(Chemical Equation Presented) A second generation total synthesis of the potent antitumor agent (+)-phorboxazole A (1) has been achieved. The cornerstone of this approach comprises a more convergent strategy, involving late-stage Stille union of a fully e
