867034-25-1

Basic information

• Product Name: 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester;tert-Butyl 4-(aminooxy)piperidine-1-carboxylate
• CAS NO: 867034-25-1
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216
• Mol File: 867034-25-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 316℃
• Flash Point: 145℃
• Appearance: /
• Density: 1.10
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester(867034-25-1)
• EPA Substance Registry System: 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester(867034-25-1)

Safety Data

• Hazardous Substances Data: 867034-25-1(Hazardous Substances Data)

Usage

General Description

4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester is a chemical compound that is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is a tert-butyl ester derivative of 4-aminooxypiperidine-1-carboxylic acid, and it is commonly used as a building block in the production of pharmaceuticals and agrochemicals. 4-Aminooxypiperidine-1-carboxylic acid tert-butyl ester is a white to off-white solid with a molecular formula of C11H21N3O4 and a molecular weight of 263.30 g/mol. It is important to handle and store this chemical compound with care, as it may have reactivity with various chemicals and it may be harmful if ingested or inhaled.

Upstream product

• 143539-99-5 tert-butyl 4-(1,3-dioxo-1,3-dihydroisoindol-2-yloxy)piperidine-1-carboxylate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 1200798-07-7 tert-butyl 4-(3-(4-fluorophenyl)ureidooxy)piperidine-1-carboxylate 
• 1393685-92-1 4-[4-(4-amino-2,5-difluorophenyl)cyclohexylideneaminooxy]piperidin-1-carboxylic acid isopropyl ester 
• 1407965-47-2 4-(4-amino-2,5-difluoro-phenyl)cyclohexanone O-[1-(4-trifluoromethyl-pyrimidin-2-yl)piperidin-4-yl]oxime 
• 1393685-68-1 4-[4-(4-amino-2,5-difluorophenyl)cyclohexylideneaminooxy]piperidin-1-carboxylic acid tert-butyl ester 
• 1200798-08-8 1-(4-fluorophenyl)-3-(piperidin-4-yloxy)urea hydrochloride 
• 1200797-56-3 1-(4-fluorophenyl)-3-(1-(4-methylpiperazin-1-ylsulfonyl)piperidin-4-yloxy)urea 
• 1200797-51-8 1-(4-fluorophenyl)-3-(1-(piperidin-1-ylsulfonyl)piperidin-4-yloxy)urea 
• 1452466-03-3 tert-butyl 4-[({[(2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}amino)oxy]piperidine-1-carboxylate 
• 1163765-27-2 4-{[7-(2-fluoro-4-iodo-phenylamino)-pyrrolo[1,2-c]pyrimidine-6-carbonyl]-aminooxy}-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp3)?H Amidation

Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing a p-nitrophenyldifluoromethyl group, which 1. displays a good safety profile; 2. shows a remarkably high react

OXIME DERIVATIVES AS GPR119 AGONISTS

The present invention relates to oxime derivatives, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The oxime derivatives according to the present invention act as GPR119 agonists to stimulate the secretion of insulin and promote GLP-1 formation for preventing or treating type 2 diabetes, complications of diabetes, obesity, dyslipidemia or osteoporosis.

OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF

The invention relates to oxycarbamoyl compounds of Formula I: The invention is also directed to the use compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockadeof calcium channels, and particularly N-type calcium channe