867034-96-6

Basic information

• Product Name: 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE
• Synonyms: 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE;6-Azazindole-2-carboxyaldehyde;3-c]pyridine-2-carbaldehyde;6-Azaindole-2-carboxyaldehyde;6-Azaindole-2-carbaldehyde;1H-Pyrrolo[2,3-c]pyridine-2-carboxaldehyde
• CAS NO: 867034-96-6
• Molecular Formula: C₈H₆N₂O
• Molecular Weight: 146.15
• Mol File: 867034-96-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE(867034-96-6)
• EPA Substance Registry System: 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE(867034-96-6)

Safety Data

• Hazardous Substances Data: 867034-96-6(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-c]pyridine-2-carbaldehyde, also known as acridine yellow, is a heterocyclic compound with a fused pyrrole and pyridine ring structure. It is commonly used as a reactant in the synthesis of pharmaceuticals and other organic compounds due to its versatile chemical properties. 1H-PYRROLO[2,3-C]PYRIDINE-2-CARBALDEHYDE is also used as a pH indicator and in the production of fluorescent dyes. It has been found to have potential antimicrobial and antitumor activities, making it a subject of interest in medical and pharmaceutical research. Additionally, it is known for its strong fluorescent properties, making it useful in various biochemical and analytical applications.

Downstream Products

• 25957-70-4 1-acetyl-3-(5-oxo-2-phenyl-oxazol-4-ylidenemethyl)-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).

2 - (AZAINDOL- 2 -YL) BENZ IMIDAZOLES AS PAD4 INHIBITORS

Compounds of formula (I) wherein; R1 is hydrogen or C1-6alkyl; R2 is hydrogen, C1-6alkyl, perhalomethylC0-5alkyl-O-, or C1-6alkoxy; R3 is hydrogen, C1-6alkyl, or C1-6alkoxyC1-6alkyl; R4 is hydrogen, C1-6alkyl, perhalomethylC1-6alkyl; or unsubstituted C3-6cycloalkylC1-6alkyl; A is C-R5 or N; B is C-R6 or N; D is C-R7 or N; with the proviso that at least one of A, B, and D, is N; R5 is hydrogen or C1-6alkyl; R6 is hydrogen or C1-6alkyl; R7 is hydrogen, C1-6alkyl, C1-6alkoxy, or hydroxy; R8 is hydrogen or C1-6alkyl, with the proviso that one of R4 and R8 is hydrogen; R9 is hydrogen or hydroxy; R10 is hydrogen or C1-6alkyl; and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis.