86704-37-2Relevant academic research and scientific papers
Muramyldipeptide derivatives
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, (2008/06/13)
Muramyldipeptide derivatives represented by the formula: STR1 wherein Ala represents alanine; Acyl represents an acyl group; R1 and R2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R3 represents a hydrogen atom, an acyl group or an alkyl group; and R4 represents a hydrogen atom or an alkyl group. These compounds have excellent immunoadjuvant activity, prophylactic and therapeutic effects against microbial infections, and antitumor activity.
Synthesis and biological activities of N-acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine and some of its lipophilic derivatives.
Hasegawa,Hioki,Kiso,Okumura,Azuma
, p. 183 - 199 (2007/10/02)
N-Acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine and some lipophilic analogs were synthesized from benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-3-O-[D-1-(methoxycarbonyl)ethyl ]- alpha-D-glucopyranoside (1). O-Debenzoylation of 2, derived from 1 by oxid
