867154-52-7Relevant academic research and scientific papers
Enantioselective synthesis of (+)(R)- And (-)(S)-nicotine based on Ir-catalysed allylic amination
Welter, Carolin,Moreno, Rosa M.,Streiff, Stephane,Helmchen, Guenter
, p. 3266 - 3268 (2005)
The synthesis of nicotine with enantiomeric excess of >99% ee was accomplished by asymmetric Ir-catalysed allylic amination followed by ring closing metathesis and racemisation-free double bond reduction. The Royal Society of Chemistry 2005.
