86716-96-3

Upstream product

• 133764-68-8 6,8-dibromo-2-Me-3-(4-nitrophenyl)-1,3-quinazolin-4(H)-one 
• 40889-42-7 6,8-dibromo-2-methyl-3,1-benzoxazin-4(H)-one 
• 100-01-6 4-nitro-aniline 
• 106-50-3 1,4-phenylenediamine 
• 609-85-8 2-amino-3,5-dibromobenzoic acid 

Downstream Products

• 86716-47-4 N-({N'-[4-(6,8-Dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-phenyl]-guanidino}-imino-methyl)-4-methyl-benzenesulfonamide; hydrochloride 
• 86716-48-5 N-({N'-[4-(6,8-Dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-phenyl]-guanidino}-imino-methyl)-4-methoxy-benzenesulfonamide; hydrochloride 
• 86716-49-6 N-{4-[({N'-[4-(6,8-Dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-phenyl]-guanidino}-imino-methyl)-sulfamoyl]-phenyl}-acetamide; hydrochloride 
• 86716-46-3 N-({N'-[4-(6,8-Dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-phenyl]-guanidino}-imino-methyl)-benzenesulfonamide; hydrochloride 
• 133764-72-4 6,8-dibromo-2-Me-3-<4-(N¹-p-chlorophenylthiourea-N³-yl)phenyl>-1,3-quinazolin-4(4H)-one 
• 1374601-11-2 1-(4-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)urea 

Relevant academic research and scientific papers

Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4- oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivatives

Novel quinazolinone derivatives 5a-5n were designed, synthesized and screened for antiepileptic activity using MES and scPTZ seizures tests. Neurotoxicity study was performed by rotorod test. Compounds 5c, 5d, 5g, 5j and 5k were found active in the prelim