867164-54-3

Basic information

• Product Name: Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
• Synonyms: 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-2-phenylquinoline;2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)quinoline;Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
• CAS NO: 867164-54-3
• Molecular Formula: C₂₁H₂₂BNO₂
• Molecular Weight: 331.21588
• Mol File: 867164-54-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-(867164-54-3)
• EPA Substance Registry System: Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-(867164-54-3)

Safety Data

• Hazardous Substances Data: 867164-54-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for various chemical reactions, facilitating the synthesis of a wide range of organic compounds.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- may serve as a key intermediate in the development of new drugs. Its quinoline and phenyl moieties, along with the boron-containing group, could be leveraged to design molecules with specific biological activities, targeting various therapeutic areas.
Used as a Reagent in Chemical Reactions:
Quinoline, 2-phenyl-7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)can be utilized as a reagent in specific chemical reactions, such as cross-coupling reactions, where the boron-containing group may participate in the formation of new carbon-carbon or carbon-heteroatom bonds, contributing to the synthesis of desired products.

Upstream product

• 61687-26-1 7-chloro-2-phenyl-quinoline 
• 73183-34-3 bis(pinacol)diborane 
• 867164-56-5 trifluoromethanesulfonic acid 2-phenylquinolin-7-yl ester 

Downstream Products

• 867160-71-2 linsitinib 
• 1356958-93-4 cis-8-amino-3-(3-hydroxy-3-methyl-cyclobutyl)-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-7-ium methanesulfonate 
• 1356958-77-4 cis-8-amino-3-(3-hydroxy-3-methyl-cyclobutyl)-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-7-ium chloride 
• 867164-35-0 cis-3-[3-(4-methyl-piperazin-1-yl)-cyclobutyl]-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-8-ylamine 

Relevant articles and documents

6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS

Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein XI, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.