867181-98-4 Usage
Uses
Used in Organic Synthesis:
(+/-)-1-acetamido-1-(2-methylphenyl)methaneboronic acid is used as a synthetic intermediate for the preparation of various organic compounds. Its boronic acid functionality allows it to participate in a range of reactions, such as Suzuki-Miyaura cross-coupling, which is a widely used method for the formation of carbon-carbon bonds. This makes it a valuable component in the synthesis of complex organic molecules and pharmaceuticals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (+/-)-1-acetamido-1-(2-methylphenyl)methaneboronic acid is used as a building block for the development of new pharmaceutical agents. Its unique structure and reactivity can be leveraged to design and synthesize bioactive molecules with potential therapeutic applications. The chiral nature of the compound may also be important for the development of enantioselective drugs, where one enantiomer may exhibit desired biological activity while the other may not.
Used in Chemical Research:
(+/-)-1-acetamido-1-(2-methylphenyl)methaneboronic acid is utilized in chemical research to explore new reaction mechanisms and develop innovative synthetic methods. Its unique properties and reactivity can provide insights into the behavior of boronic acids and related compounds, contributing to the advancement of organic chemistry.
Used in Materials Science:
In materials science, (+/-)-1-acetamido-1-(2-methylphenyl)methaneboronic acid may be employed in the development of new materials with specific properties. Its ability to form stable covalent bonds and its potential to interact with other molecules could be harnessed to create materials with tailored characteristics for various applications, such as sensors, catalysts, or advanced materials for electronics and energy storage.
Check Digit Verification of cas no
The CAS Registry Mumber 867181-98-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,1,8 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 867181-98:
(8*8)+(7*6)+(6*7)+(5*1)+(4*8)+(3*1)+(2*9)+(1*8)=214
214 % 10 = 4
So 867181-98-4 is a valid CAS Registry Number.
867181-98-4Relevant academic research and scientific papers
Enantiomeric excess of 1,2-diols by formation of cyclic boronates: An improved method
Morandi, Stefania,Caselli, Emilia,Forni, Arrigo,Bucciarelli, Maria,Torre, Giovanni,Prati, Fabio
, p. 2918 - 2926 (2007/10/03)
A reliable method for determining the enantiomeric composition of 1,2-diols by the formation of diastereomeric cyclic esters with boronic acid is described. Starting from a previously reported structure of boronic chiral derivatizing agent (CDA), seven structurally related racemic CDAs were synthesized and their discriminating ability towards diols measured. The most promising amongst these was synthesized in its enantiomerically pure form according to Matteson's protocol for the stereoselective homologation of pinanediol boronates; this CDA quantitatively and rapidly reacts with 1,2-diols in very mild conditions affording a couple of diastereoisomers, whose composition can be determined via 1H NMR analysis. In particular, an attractive feature is that the resonance used for the analysis originated from the CDA as a couple of baseline-separated singlets (Δδ up to 0.3 ppm) is useful for integration.
