867216-81-7

Basic information

• Product Name: 3-(2,6-dichlorophenyl)-5-[4-[2-(4-fluorobenzoyl)ethyl]amino-2-pyridyl]isoxazole
• Synonyms: 3-(2,6-dichlorophenyl)-5-[4-[2-(4-fluorobenzoyl)ethyl]amino-2-pyridyl]isoxazole
• CAS NO: 867216-81-7
• Molecular Weight: 456.303
• Mol File: 867216-81-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2,6-dichlorophenyl)-5-[4-[2-(4-fluorobenzoyl)ethyl]amino-2-pyridyl]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,6-dichlorophenyl)-5-[4-[2-(4-fluorobenzoyl)ethyl]amino-2-pyridyl]isoxazole(867216-81-7)
• EPA Substance Registry System: 3-(2,6-dichlorophenyl)-5-[4-[2-(4-fluorobenzoyl)ethyl]amino-2-pyridyl]isoxazole(867216-81-7)

Safety Data

• Hazardous Substances Data: 867216-81-7(Hazardous Substances Data)

Upstream product

• 867215-91-6 2-(3-(2,6-dichlorophenyl)isoxazol-5-yl)pyridin-4-amine 
• 347-93-3 3-chloro-4'-fluoropropiophenone 

Downstream Products

• 867216-82-8 2',2'-dichloro-N-[2-[3-(2,6-dichlorophenyl)-5-isoxazolyl]-(4-pyridyl)]-N-[2-(4-fluorobenzoyl)ethyl]acetamide 

Relevant articles and documents

HETEROCYCLIC ANTI-VIRAL COMPOUNDS COMPRISING METABOLIZABLE MOIETIES AND THEIR USES

The present invention relates to substituted prodrug and compositions thereof useful for treating or preventing Hepatitis C virus (HCV) infections. In particular, the present invention relates to prodrugs of substituted diphenyl-, diheteroaryl- and mixed phenyl heteroaryl substituted five-membered heterocycle compounds, compositions comprising the compounds and the use of such compounds and compositions to inhibit HCV replication and/or proliferation as a therapeutic approach towards the treatment and/or prevention of HCV infections in humans and animals.