867259-40-3

Basic information

• Product Name: 4(1H)-Pyrimidinone, 2-amino-6-[[3,5-bis(hydroxymethyl)phenyl]amino]-5-(phenylazo)-
• CAS NO: 867259-40-3
• Molecular Formula: C18H18N6O3
• Molecular Weight: 366.379
• Mol File: 867259-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyrimidinone, 2-amino-6-[[3,5-bis(hydroxymethyl)phenyl]amino]-5-(phenylazo)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 2-amino-6-[[3,5-bis(hydroxymethyl)phenyl]amino]-5-(phenylazo)-(867259-40-3)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 2-amino-6-[[3,5-bis(hydroxymethyl)phenyl]amino]-5-(phenylazo)-(867259-40-3)

Safety Data

• Hazardous Substances Data: 867259-40-3(Hazardous Substances Data)

Upstream product

• 71176-54-0 (3-amino-5-hydroxymethylphenyl)methanol 
• 30412-45-4 2-amino-4-chloro-6-hydroxy-5-phenylazopyrimidine 

Downstream Products

• 867259-41-4 2-amino-4-[3,5-bis(tert-butyldimethylsilanyloxymethyl)anilino]-6-hydroxy-5-phenylazopyrimidine 
• 867259-44-7 9-[3-(4,4'-dimethoxytrityloxymethyl)-5-(hydroxymethyl)phenyl]-2-N-[(dimethylamino)methylene]guanine 
• 867259-42-5 9-[3,5-bis(tert-butyldimethylsilanyloxymethyl)phenyl]-2-N-[(dimethylamino)methylene]guanine 
• 867259-43-6 9-[3-(tert-butyldimethylsilanyloxymethyl)-5-(hydroxymethyl)phenyl]-2-N-[(dimethylamino)methylene]guanine 

Relevant articles and documents

Synthesis and properties of nucleic acid analogues consisting of a benzene-phosphate backbone

The synthesis and properties of a nucleic acid analogue consisting of a benzene-phosphate backbone are described. The building blocks of the nucleic acid analogue are composed of bis(hydroxymethyl)-benzene residues connected to nucleobases via the biaryl-like axis. Stabilities of the duplexes were studied by thermal denaturation. It was found that the thermal stabilities of the duplexes composed of the benzene-phosphate backbone are highly dependent on their sequences. The duplexes with the benzene-phosphate backbone comprised of the mixed sequences were thermally less stable than the natural DNA duplexes, whereas that composed of the homopyrimidine and homopurine sequences was thermally and thermodynamically more stable than the corresponding natural DNA duplex. It was suggested that the analogues more efficiently stabilize the duplexes in a B-form duplex rather than in an A-form duplex. Thus, the duplexes consisting of the benzene-phosphate backbone, especially composed of the homopyrimidine and homopurine sequences, may offer a novel structural motif useful for developing novel materials applicable in the fields of bio- and nanotechnologies.