867309-17-9

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 4949-69-3 4-iodo-3-methylaniline 
• 74-88-4 methyl iodide 

Downstream Products

• 1011801-26-5 1-methyl-3-(N-methyl-N-tosyl)-5,6-dihydro-9-chloro-10-azaindolo[2,1-a]isoquinoline 
• 1011801-48-1 5,6-dihydro-N,10-dimethyl-N-tosylpyrazolo[5,1-a]isoquinolin-8-amine 

Relevant academic research and scientific papers

Palladium-Catalyzed Norbornene-Mediated Tandem Amination/Cyanation Reaction: A Method for the Synthesis of ortho-Aminated Benzonitriles

A palladium-catalyzed, norbornene-mediated tandem amination/cyanation reaction via Catellani-type C-H functionalization was developed using N-benzoyloxyamines as the amination reagent and Zn(CN)2 as the terminating agent. This transformation, in which one C-N bond and one C-C bond are formed, provides an efficient approach for the synthesis of ortho-aminated benzonitriles in one pot from easily accessible starting materials.

Decarboxylative Alkynyl Termination of Palladium-Catalyzed Catellani Reaction: A Facile Synthesis of α-Alkynyl Anilines via Ortho C - H Amination and Alkynylation

A palladium-catalyzed synthesis of α-alkynyl anilines is reported. The reaction proceeds via Catellani ortho C-H amination followed by decarboxylative alkynylative amination. Different terminal alkyne precursors were screened, and it was found that alkyny

A route to annulated indoles via a palladium-catalyzed tandem alkylation/direct arylation reaction

A norbornene-mediated palladium-catalyzed tandem alkylation/C-H functionalization sequence is described, in which an alkyl-aryl bond and a heteroaryl-aryl bond are formed in one pot. A variety of highly substituted six- and seven-membered ring annulated i