86775-99-7

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(2-Bromoanilino)pyridine is used as an intermediate in the synthesis of pharmaceuticals for its ability to participate in coupling reactions and organic transformations, contributing to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, 4-(2-Bromoanilino)pyridine is used as a reagent or building block for the creation of complex organic molecules, taking advantage of its bromoanilino group to facilitate specific chemical reactions.
Used in Medicinal Chemistry:
4-(2-Bromoanilino)pyridine is utilized in medicinal chemistry as a component in the design and synthesis of potential drug candidates, leveraging its unique structure to explore novel therapeutic agents.
Used in Material Science:
In material science, 4-(2-Bromoanilino)pyridine may be employed in the development of new materials, potentially due to its reactivity and the properties conferred by its molecular structure.

InChI:InChI=1S/C11H9BrN2/c12-10-3-1-2-4-11(10)14-9-5-7-13-8-6-9/h1-8H,(H,13,14)

Upstream product

• 504-24-5 4-aminopyridine 
• 583-55-1 1-Bromo-2-iodobenzene 

Downstream Products

• 1015460-56-6 8-bromo-5H-pyridine[4,3-b]indole 

Relevant academic research and scientific papers

Organic light-emitting device

The present invention relates to an organic light emitting device having excellent electrical properties and thermal stability, which comprises: a first electrode; a second electrode; and an organic layer disposed between the first and second electrodes,

ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING CARBOLINE GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME

An organic electroluminescent material is shown in General Formula (1), wherein R3 is a carboline group, R13 is a carbazole group or a carboline group, R1 to R2, R4 to R12 and R14 to R20 are each independently selected from the group consisting of a hydrogen atom, a fluorine atom, a cyano group, an alkyl group, a cycloalkyl group, an alkoxy group, a haloalkyl group, a thioalkyl group, a silyl group and an alkenyl group.

A pyrimidine derivatives and application thereof (by machine translation)

The invention discloses a pyrimidine derivative and its application, the pyrimidine derivatives having the following -like type (I) indicated by the structure; wherein said R1 , R2 , R3 Are selected from the carbon atom number is 1 - 60 alkyl, substituted and non-substituted aromatic heterocyclic radical, and substituted and non-substituted aromatic ring in base of any one group. The invention through the pyrimidine derivatives key chemical structure and the like is improved, and the pyrimidine derivatives as material is applied to the electro-luminescent layer in the organic electroluminescent device, compared with the prior art can effectively solve the organic electroluminescent device in blue light material of poor stability, low efficiency and the like. (by machine translation)

ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING N-PHENYLCARBOLINE AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME

An organic electroluminescent material is shown in General Formula (1), wherein one of X1, X2, and X3 is an independent nitrogen atom, and R1 to R14 are each independently selected from the group consisting of a hydrogen atom, a fluorine atom, a cyano group, an alkyl group, a cycloalkyl group, an alkoxy group, a thioalkyl group, a silyl group, and an alkenyl group.

Effect of the position of nitrogen in pyridoindole on photophysical properties and device performances of α-, β-, γ-carboline based high triplet energy host materials for deep blue devices

Three carboline derivatives with nitrogen at different positions of the pyridoindole unit were synthesized and the effect of the position of nitrogen on the photophysical properties and device performances was investigated. β-Carboline was effective in obtaining high triplet energy and stabilizing energy levels, while α-carboline was better than other carbolines in terms of quantum efficiency. However, γ-carboline could not stabilize the LUMO level and low quantum efficiency was obtained.

γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity

Based on anti-viral screening of our heteroaromatics derived from thalidomide, the γ-carboline skeleton has been identified as a superior scaffold structure for compounds with potent anti-bovine viral diarrhea virus (BVDV) activity. Structural development studies led to a potent anti-viral agent, SK5M (5-methyl-γ-carboline), with the EC50 of 0.26 μM.

Novel synthetic strategy of carbolines via palladium-catalyzed amination and arylation reaction

Four parent carbolines and the corresponding 5- or 9-methylsulfonyl derivatives were synthesized by the palladium-catalyzed intramolecular arylation reaction of ortho-bromo-substituted anilinopyridines which were prepared by the palladium-catalyzed amination reaction of iodobenzenes with aminopyridines. Carbazole and its 9-methylsulfonyl derivative were also synthesized by the same method.

Synthetic Applications of N-N Linked Heterocycles. Part 15. A Facile Synthesis of 4-Pyridyl(aryl)amines via the Reaction between 4-Chloro-1-pyridiniopyridinium Salts and Aryl Amines

4-Chloro-1-pyridiniopyridinium salts (7) and (8) react with primary and secondary arylamines to give high yields of isolable 4-aryliminium salts (9) and (10).These are readily fragmented into 4-pyridyl(aryl)amines (11) and (12) in excellent yields on treatment with sodium cyanide or sodium salts of sulphonic acids.The method fails with the more basic aliphatic amines, since these apparently attack the 2-position of the chloropyridinium ring giving products resulting from ring-opening.Mechanisms of the reactions are discussed.