86785-85-5

Upstream product

• 1629-58-9 4-penten-3-one 
• 583-60-8 2-Methylcyclohexanone 
• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 
• 107957-68-6 3-methoxy-2-pentene-1-ol 

Downstream Products

• 878-55-7 1,4a-dimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one 
• 20591-69-9 (+/-)-3,4,4aα,5,6,7,8aα-octahydro-8aβ-hydroxy-1β,4aα-dimethyl-2(1H)-naphthalenone 
• 20591-69-9 (+/-)-3,4,4aα,5,6,7,8aα-octahydro-8aα-hydroxy-1β,4aα-dimethyl-2(1H)-naphthalenone 
• 20591-69-9 (+/-)-3,4,4aα,5,6,7,8aα-octahydro-8aα-hydroxy-1α,4aα-dimethyl-2(1H)-naphthalenone 

Relevant academic research and scientific papers

145. Stereochemistry of the Robinson Anellation: Studies on the Mode of Formation of the Intermediate Hydroxy Ketones

The stereochemical outcome of the base-catalyzed cyclization of diketones 5-8 has been investigated under protic conditions (Scheme 3).The more stable trans-fused ketols are preferentially formed in kinetically controlled aldol reactions, when the incipie

1,5-DICARBONYL COMPOUNDS A GENERAL PREPARATION METHOD

In this report, a general method for the preparation of 1,5-dicarbonyl compounds and six membered ring annelation is described.This method involves the reaction of hemiacetal vinylogs 1 with enol ethers 2 or 3 in the presence of a Lewis acid.This reaction was successfully applied to the enol ethers of α and α,α'-hindered ketones such as 2,2,6-trimethyl cyclohexanone. α-Cyperone and 6-epi-α-cyperone were obtained using this process.