86795-01-9Relevant articles and documents
Design and validation of FRESH, a drug discovery paradigm resting on robust chemical synthesis
Shi, Qi,Kaiser, Thomas M.,Dentmon, Zackery W.,Ceruso, Mariangela,Vullo, Daniela,Supuran, Claudiu T.,Snyder, James P.
, p. 518 - 522 (2015)
A method capable of identifying novel synthetic targets for small molecule lead optimization has been developed. The FRESH (FRagment-based Exploitation of modular Synthesis by vHTS) approach relies on a multistep synthetic route to a target series of comp
