86795-01-9Relevant academic research and scientific papers
Design and validation of FRESH, a drug discovery paradigm resting on robust chemical synthesis
Shi, Qi,Kaiser, Thomas M.,Dentmon, Zackery W.,Ceruso, Mariangela,Vullo, Daniela,Supuran, Claudiu T.,Snyder, James P.
, p. 518 - 522 (2015)
A method capable of identifying novel synthetic targets for small molecule lead optimization has been developed. The FRESH (FRagment-based Exploitation of modular Synthesis by vHTS) approach relies on a multistep synthetic route to a target series of comp
CARBONIC ANHYDRASE INHIBITORS AND USES RELATED THERETO
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Page/Page column 21, (2016/10/11)
In certain embodiments, this disclosure relates to carbonic anhydrase inhibitors that are phenylureidobenzenesulfonamide derivatives and uses related thereto. In certain embodiments, the phenylureidobenzenesulfonamide derivatives are of Formula I, wherein
