86795-60-0Relevant articles and documents
Ylides of Heterocycles, IV. Sulfonium- and Pyridinium-Ylides of Coumarin and 2-Quinolone
Kappe, Thomas,Korbuly, Gertraud,Pongratz, Erik
, p. 303 - 316 (1983)
The title compounds 3 can be prepared either from the iodonium-ylides 1 or from the chlorocompounds 4.On treatment with hydrochloric acid the thiophanium-ylides 3C undergo ring cleavage to the chlorobutylsulfides 5, also formed from 4 and thiophane.The dimethylsulfonium-ylide 8 is derived from activated DMSO and 7b.The Ortoleva-King reaction is discussed as an alternative method for preparing pyridiniumylides. - Keywords: Activated dimethylsulfoxide; Ortoleva-King reaction; 2-Oxobenzopyran-4-olates; 2-Oxoquinolin-4-olates; Thiophanium ylides
4-hydroxy-2-quinolones. 31. 3-amino-1R-2-oxo-4-hydroxyquinolines and their acyl derivatives
Ukrainets,Taran,Sidorenko,Gorokhova,Ogirenko,Turov,Filimonova
, p. 960 - 970 (2007/10/03)
An alternative method has been developed for preparing and studying the antioxidant activity of 3-acylamino-2-oxo-4-hydroxyquinolones. Results are presented from an investigation of the antithyroid and antimicrobial action of the intermediate 2-oxo-3-(1-pyridinio)quinolin-4-olates and the 3-amino-2-oxo-4-hydroxyquinolines. 1997 Plenum Publishing Corporation.
Ylides of Heterocycles, III. Pyridinium Ylides of Malonylheterocycles
Kappe, Thomas,Hariri, Mehdi,Pongratz, Erik
, p. 1211 - 1220 (2007/10/02)
Reaction of isatoic anhydride with the betaine esters 2 or 3 represents a new synthesis of pyridinium ylides of type 5, which have been previously obtained by several other ways.Treatment of the ylide 5 with inorganic acids results in the formation of their pyridinium salts 5a-d.Hydrogenation or dehydrogenation of 5 with Pd/C give the piperidylquinoline 9 or the betaine 10, respectively.Both of them can be prepared by an alternative way.The pK values of some pyridinium ylides were determined. - Keywords: Cyclodehydrogenation; Isatoic anhydride; Palladium; pK Values; Pyridiniummalonate betaine; Pyridinium ylides of quinolinediones